The VMESCmodule2 represents the pinnacle of VME system controller technology, acting as a pivotal link between VME and AXI bus architectures. It integrates advanced functionalities like programmable interrupters and multiple arbitration techniques to optimize system throughput and responsiveness. Key features include an 8-window VME Slave, a capable VME Master, and sophisticated support for programmable interrupt handling. The inclusion of mechanisms for prioritized and round-robin arbitration make it highly versatile, suitable for complex and large-scale systems. This module stands as an ideal choice for developers looking to infuse their designs with robust VME connectivity coupled with AXI benefits. Widely applicable in sectors like telecommunications and industrial automation, the VMESCmodule2 is known for its reliability and efficiency, promoting enhanced interconnectivity in diverse technological ecosystems. Designed for both legacy support and modern enhancements, it ensures the seamless operation of integrated systems.