Emphasizing lossless efficiency, the JPEG-LS IP core offers a streamlined approach to image compression, perfect for applications requiring error-free data reduction, like medical imaging and archival storage. Built on the LOCO-I algorithm, it achieves compression with minimal resource overhead, crucial for maintaining data integrity. It effectively reduces image data sizes while ensuring no loss in information quality, supporting various data depths and configurations, making it versatile for numerous deployment environments. With a focus on reducing operational complexity, the JPEG-LS core is highly adaptable, fitting well in scenarios prioritizing uncompromised image quality and storage efficiency over extensive processing output.